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I have a Lap Band. Before I had the band I had no problem with heartburn, then after I got a couple adjustments, I had acid reflux and heartburn so bad I was eating like 20 Tums a day. Zantac no longer works, or anything for that matter, so I went to my doctor and he gave me samples of Protonix. Within minutes my heartburn was gone. I have slept through the night without vomiting my own stomach acid. Highly recommend this drug. If you have a Lap band then you know how horrible it can be.

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Under maximal acid stimulatory conditions using pentagastrin, a dose-dependent decrease in gastric acid output occurs after a single dose of oral (20 to 80 mg) Pantoprazole in healthy volunteers.

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Reflux disease: Gastrooesophageal reflux disease in adults.

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The pharmacokinetics of PROTONIX Delayed-Release Tablets were evaluated in children ages 6 through 16 years with a clinical diagnosis of GERD.

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It is used to treat gastroesophageal reflux disease (GERD), inflammation of the esophagus, and Zollinger-Ellison syndrome.

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Atrophic GastritisAtrophic gastritis has been noted occasionally in gastric corpus biopsies from patients treated long-term with pantoprazole sodium delayed-release tablets, particularly in patients who were positive.

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Following development of the chromatographic system for pantoprazole, the suitability of this method for use as a stability-indicating assay was tested by running samples of pantoprazole that had been subjected to accelerated degradation.

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